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Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-α as an effective therapeutic vaccine adjuvant

Chronic hepatitis B virus (CHB) infection is a significant public threat. Current interferon-α (IFN-α) based therapies and anti-viral drugs have failed to clear the infection in the majority of CHB patients and animal models. In our previous study, we established a combined protocol that employed a...

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Detalles Bibliográficos
Autores principales: Zhao, Weidong, Zhao, Gan, Zhang, Shuren, Wang, Xianzheng, Yu, Xueping, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188151/
https://www.ncbi.nlm.nih.gov/pubmed/30344938
http://dx.doi.org/10.18632/oncotarget.25789