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Clearance of HBeAg and HBsAg of HBV in mice model by a recombinant HBV vaccine combined with GM-CSF and IFN-α as an effective therapeutic vaccine adjuvant
Chronic hepatitis B virus (CHB) infection is a significant public threat. Current interferon-α (IFN-α) based therapies and anti-viral drugs have failed to clear the infection in the majority of CHB patients and animal models. In our previous study, we established a combined protocol that employed a...
Autores principales: | Zhao, Weidong, Zhao, Gan, Zhang, Shuren, Wang, Xianzheng, Yu, Xueping, Wang, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188151/ https://www.ncbi.nlm.nih.gov/pubmed/30344938 http://dx.doi.org/10.18632/oncotarget.25789 |
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