Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels

BACKGROUND: Tumor vessels were persistently compressed by solid stress from tumor interstitial matrix, resulting in limited vessel perfusion and oxygen concentrations. Collagen within matrix participated in transmitting the solid stress to tumor vessels and limiting drug delivery. PURPOSE: The objec...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoxu, Pan, Jinghua, Li, Wei, Yang, Wende, Qin, Li, Pan, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188185/
https://www.ncbi.nlm.nih.gov/pubmed/30349245
http://dx.doi.org/10.2147/IJN.S176928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188185/
https://www.ncbi.nlm.nih.gov/pubmed/30349245
http://dx.doi.org/10.2147/IJN.S176928

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