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Nanotechnology, from quantum mechanical calculations up to drug delivery

There are several reasons why nanotechnology is currently considered as the leader among the most intensively developing research trends. Nanomatter often exhibits new properties, other than those of the morphology of a continuous solid. Also, new phenomena appear at the nanoscale, which are unknown...

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Autor principal: Szefler, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188196/
https://www.ncbi.nlm.nih.gov/pubmed/30349242
http://dx.doi.org/10.2147/IJN.S172907
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author Szefler, Beata
author_facet Szefler, Beata
author_sort Szefler, Beata
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description There are several reasons why nanotechnology is currently considered as the leader among the most intensively developing research trends. Nanomatter often exhibits new properties, other than those of the morphology of a continuous solid. Also, new phenomena appear at the nanoscale, which are unknown in the case of microcrystalline objects. For this reason, nanomaterials have already found numerous applications that are described in this review. However, among intensively developed various branches of nanotechnology, nanomedicine and pharmacology stand out particularly, which opens new possibilities for the development of these disciplines, gives great hope for the creation of new drugs in which toxicological properties are reduced to a minimum, reduces the doses of medicines, offers targeted treatment and increases diagnostic possibilities. Nanotechnology is the source of a great revolution in medicine. It gives great hope for better and faster treatment of many diseases and gives hope for a better tomorrow. However, the creation of new “nanodrugs” requires a special understanding of the properties of nanoparticles. This article is a review work which determines and describes the way of creating new nanodrugs from ab initio calculations by docking and molecular dynamic applications up to a new medicinal product, as a proposal for the personalized medicine, in the early future.
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spelling pubmed-61881962018-10-22 Nanotechnology, from quantum mechanical calculations up to drug delivery Szefler, Beata Int J Nanomedicine Review There are several reasons why nanotechnology is currently considered as the leader among the most intensively developing research trends. Nanomatter often exhibits new properties, other than those of the morphology of a continuous solid. Also, new phenomena appear at the nanoscale, which are unknown in the case of microcrystalline objects. For this reason, nanomaterials have already found numerous applications that are described in this review. However, among intensively developed various branches of nanotechnology, nanomedicine and pharmacology stand out particularly, which opens new possibilities for the development of these disciplines, gives great hope for the creation of new drugs in which toxicological properties are reduced to a minimum, reduces the doses of medicines, offers targeted treatment and increases diagnostic possibilities. Nanotechnology is the source of a great revolution in medicine. It gives great hope for better and faster treatment of many diseases and gives hope for a better tomorrow. However, the creation of new “nanodrugs” requires a special understanding of the properties of nanoparticles. This article is a review work which determines and describes the way of creating new nanodrugs from ab initio calculations by docking and molecular dynamic applications up to a new medicinal product, as a proposal for the personalized medicine, in the early future. Dove Medical Press 2018-10-09 /pmc/articles/PMC6188196/ /pubmed/30349242 http://dx.doi.org/10.2147/IJN.S172907 Text en © 2018 Szefler. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Szefler, Beata
Nanotechnology, from quantum mechanical calculations up to drug delivery
title Nanotechnology, from quantum mechanical calculations up to drug delivery
title_full Nanotechnology, from quantum mechanical calculations up to drug delivery
title_fullStr Nanotechnology, from quantum mechanical calculations up to drug delivery
title_full_unstemmed Nanotechnology, from quantum mechanical calculations up to drug delivery
title_short Nanotechnology, from quantum mechanical calculations up to drug delivery
title_sort nanotechnology, from quantum mechanical calculations up to drug delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188196/
https://www.ncbi.nlm.nih.gov/pubmed/30349242
http://dx.doi.org/10.2147/IJN.S172907
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