Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro

BACKGROUND: Although asparagine synthetase (AsnS) is associated with drug resistance in leukemia, its function in extranodal natural killer (NK)/T-cell lymphoma (ENKTL) remains unclear. METHODS: The present study investigated the relationship between baseline AsnS mRNA levels and response to asparag...

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Detalles Bibliográficos
Autores principales: Liu, Wen-jian, Wang, Hua, Peng, Xiong-wen, Wang, Wei-da, Liu, Na-wei, Wang, Yang, Lu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188207/
https://www.ncbi.nlm.nih.gov/pubmed/30349294
http://dx.doi.org/10.2147/OTT.S155930

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