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Calcium binding of the antifungal protein PAF: Structure, dynamics and function aspects by NMR and MD simulations

Calcium ions (Ca(2+)) play an important role in the toxicity of the cysteine-rich and cationic antifungal protein PAF from Penicillium chrysogenum: high extracellular Ca(2+) levels reduce the toxicity of PAF in the sensitive model fungus Neurospora crassa in a concentration dependent way. However, l...

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Detalles Bibliográficos
Autores principales:	Fizil, Ádám, Sonderegger, Christoph, Czajlik, András, Fekete, Attila, Komáromi, István, Hajdu, Dorottya, Marx, Florentine, Batta, Gyula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188699/ https://www.ncbi.nlm.nih.gov/pubmed/30321182 http://dx.doi.org/10.1371/journal.pone.0204825

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