SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA

MITA (also called STING) is a central adaptor protein in innate immune response to cytosolic DNA. Cellular trafficking of MITA from the ER to perinuclear microsomes after DNA virus infection is critical for MITA activation and onset of innate antiviral response. Here we found that SNX8 is a componen...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Jin, Lian, Huan, Guo, Wei, Chen, Yun-Da, Zhang, Xia-Nan, Zang, Ru, Zhong, Li, Yang, Qing, Hu, Ming-Ming, Luo, Wei-Wei, Shu, Hong-Bing, Li, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188873/
https://www.ncbi.nlm.nih.gov/pubmed/30321235
http://dx.doi.org/10.1371/journal.ppat.1007336

Ejemplares similares

Ejemplares similares