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Successful Management of Giant Placental Chorangioma by Microcoil Embolization

Optimal prenatal management of giant placental chorangioma (also known as chorioangioma, angiomyxoma, fibroangiomyxoma, or fibroma) has yet to be determined. Interventions intended to devascularize the tumor such as interstitial laser, bipolar coagulation, fetoscopic laser photocoagulation, and chem...

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Autores principales: Emery, Stephen P., Orons, Philip D., Bonadio, Jeffrey F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188883/
https://www.ncbi.nlm.nih.gov/pubmed/30345160
http://dx.doi.org/10.1055/s-0038-1669944
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author Emery, Stephen P.
Orons, Philip D.
Bonadio, Jeffrey F.
author_facet Emery, Stephen P.
Orons, Philip D.
Bonadio, Jeffrey F.
author_sort Emery, Stephen P.
collection PubMed
description Optimal prenatal management of giant placental chorangioma (also known as chorioangioma, angiomyxoma, fibroangiomyxoma, or fibroma) has yet to be determined. Interventions intended to devascularize the tumor such as interstitial laser, bipolar coagulation, fetoscopic laser photocoagulation, and chemical embolization have met mixed results. We report a minimally invasive, extra-amniotic approach, technically similar to cordocentesis, of microcoil embolization of the feeding vessel. These percutaneously placed microcoils initiate clot formation at the site of insertion and are unable to migrate through the tumor, thereby minimizing fetal harm by downstream embolic phenomena. Intervention at 26 and 22 weeks resulted in intraoperative fetal loss in the former and vaginal delivery at term of a healthy neonate in the latter. Preoperative, intraoperative, and placental findings are highlighted. The ease and safety of this procedure may alter the risk–benefit equation toward earlier intervention with potentially better clinical outcomes.
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spelling pubmed-61888832018-10-19 Successful Management of Giant Placental Chorangioma by Microcoil Embolization Emery, Stephen P. Orons, Philip D. Bonadio, Jeffrey F. AJP Rep Optimal prenatal management of giant placental chorangioma (also known as chorioangioma, angiomyxoma, fibroangiomyxoma, or fibroma) has yet to be determined. Interventions intended to devascularize the tumor such as interstitial laser, bipolar coagulation, fetoscopic laser photocoagulation, and chemical embolization have met mixed results. We report a minimally invasive, extra-amniotic approach, technically similar to cordocentesis, of microcoil embolization of the feeding vessel. These percutaneously placed microcoils initiate clot formation at the site of insertion and are unable to migrate through the tumor, thereby minimizing fetal harm by downstream embolic phenomena. Intervention at 26 and 22 weeks resulted in intraoperative fetal loss in the former and vaginal delivery at term of a healthy neonate in the latter. Preoperative, intraoperative, and placental findings are highlighted. The ease and safety of this procedure may alter the risk–benefit equation toward earlier intervention with potentially better clinical outcomes. Thieme Medical Publishers 2018-10 2018-10-15 /pmc/articles/PMC6188883/ /pubmed/30345160 http://dx.doi.org/10.1055/s-0038-1669944 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Emery, Stephen P.
Orons, Philip D.
Bonadio, Jeffrey F.
Successful Management of Giant Placental Chorangioma by Microcoil Embolization
title Successful Management of Giant Placental Chorangioma by Microcoil Embolization
title_full Successful Management of Giant Placental Chorangioma by Microcoil Embolization
title_fullStr Successful Management of Giant Placental Chorangioma by Microcoil Embolization
title_full_unstemmed Successful Management of Giant Placental Chorangioma by Microcoil Embolization
title_short Successful Management of Giant Placental Chorangioma by Microcoil Embolization
title_sort successful management of giant placental chorangioma by microcoil embolization
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188883/
https://www.ncbi.nlm.nih.gov/pubmed/30345160
http://dx.doi.org/10.1055/s-0038-1669944
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