Functional characterization of common BCL11B gene desert variants suggests a lymphocyte-mediated association of BCL11B with aortic stiffness

The recent genome-wide analysis of carotid–femoral pulse wave velocity (PWV) identified a significant locus within the 14q32.2 gene desert. Gene regulatory elements for the transcriptional regulator B-cell CLL/lymphoma 11B (BCL11B) are within this locus and an attractive target for the gene associat...

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Detalles Bibliográficos
Autores principales: Maskari, Raya Al, Hardege, Iris, Cleary, Sarah, Figg, Nicki, Li, Ye, Siew, Keith, Khir, Ashraf, Yu, Yong, Liu, Pentao, Wilkinson, Ian, O’Shaughnessy, Kevin, Yasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189060/
https://www.ncbi.nlm.nih.gov/pubmed/30089823
http://dx.doi.org/10.1038/s41431-018-0226-z

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