Cargando…

NBCe1 Na(+)-HCO3(-) cotransporter ablation causes reduced apoptosis following cardiac ischemia-reperfusion injury in vivo

AIM: To investigate the hypothesis that cardiomyocyte-specific loss of the electrogenic NBCe1 Na(+)-HCO(3)(-) cotransporter is cardioprotective during in vivo ischemia-reperfusion (IR) injury. METHODS: An NBCe1 (Slc4a4 gene) conditional knockout mouse (KO) model was prepared by gene targeting. Cardi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vairamani, Kanimozhi, Prasad, Vikram, Wang, Yigang, Huang, Wei, Chen, Yinhua, Medvedovic, Mario, Lorenz, John N, Shull, Gary E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2018
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189072/ https://www.ncbi.nlm.nih.gov/pubmed/30344957 http://dx.doi.org/10.4330/wjc.v10.i9.97

Ejemplares similares

RNA SEQ Analysis Indicates that the AE3 Cl(−)/HCO(3)(−) Exchanger Contributes to Active Transport-Mediated CO(2) Disposal in Heart
por: Vairamani, Kanimozhi, et al.
Publicado: (2017)

Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na(+)-HCO(3)(−) cotransporter NBCe1
por: Seki, George, et al.
Publicado: (2013)

Revisiting the Role of Ser982 Phosphorylation in Stoichiometry Shift of the Electrogenic Na(+)/qHCO(3)(−) Cotransporter NBCe1
por: Alsufayan, Thamer A., et al.
Publicado: (2021)

Cell-Type Dependent Regulation of the Electrogenic Na(+)/HCO(3)(−) Cotransporter 1 (NBCe1) by Hypoxia and Acidosis in Glioblastoma
por: Giannaki, Marina, et al.
Publicado: (2022)

Electrogenic Na/HCO(3) Cotransporter (NBCe1) Variants Expressed in Xenopus Oocytes: Functional Comparison and Roles of the Amino and Carboxy Termini
por: McAlear, Suzanne D., et al.
Publicado: (2006)

Na(+)/HCO(3)(-) cotransporter is expressed on β and α cells during rat pancreatic development
por: Cao, Li-Hua, et al.
Publicado: (2016)

Short-Term Regulation of Murine Colonic NBCe1-B (Electrogenic Na(+)/HCO(3) (−) Cotransporter) Membrane Expression and Activity by Protein Kinase C
por: May, Oliver, et al.
Publicado: (2014)

Extracellular Hco(3) (−) Dependence of Electrogenic Na/Hco(3) Cotransporters Cloned from Salamander and Rat Kidney
por: Grichtchenko, Irina I., et al.
Publicado: (2000)

Functional Roles of Electrogenic Sodium Bicarbonate Cotransporter NBCe1 in Ocular Tissues
por: Suzuki, Masashi, et al.
Publicado: (2012)

K(+)/Cl(−) cotransporter 2 (KCC2) and Na(+)/ [Formula: see text] cotransporter 1 (NBCe1) interaction modulates profile of KCC2 phosphorylation
por: Pethe, Abhishek, et al.
Publicado: (2023)

Apical electrogenic NaHCO3 cotransport. A mechanism for HCO3 absorption across the retinal pigment epithelium
Publicado: (1989)

Transport Activity of the Sodium Bicarbonate Cotransporter NBCe1 Is Enhanced by Different Isoforms of Carbonic Anhydrase
por: Schueler, Christina, et al.
Publicado: (2011)

Understanding the Physiological Role of Electroneutral Na(+)-Coupled HCO(3)(−) Cotransporter and Its Therapeutic Implications
por: Wang, Jingjing, et al.
Publicado: (2022)

Loss of the AE3 Cl(−)/HCO(−)(3) exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart
por: Prasad, Vikram, et al.
Publicado: (2013)

The choroid plexus sodium‐bicarbonate cotransporter NBCe2 regulates mouse cerebrospinal fluid pH
por: Christensen, Henriette L., et al.
Publicado: (2018)

Basolateral membrane Na/base cotransport is dependent on CO2/HCO3 in the proximal convoluted tubule
Publicado: (1987)

Hormonal regulation of the polarized function and distribution of Na/H exchange and Na/HCO3 cotransport in cultured mammary epithelial cells
Publicado: (1993)

Lack of Charge Interaction in the Ion Binding Site Determines Anion Selectivity in the Sodium Bicarbonate Cotransporter NBCe1
por: Lee, Soojung, et al.
Publicado: (2022)

Effects of Nt-truncation and coexpression of isolated Nt domains on the membrane trafficking of electroneutral Na(+)/HCO(3)(–) cotransporters
por: Wang, Deng-Ke, et al.
Publicado: (2015)

Bicarbonate-Independent Sodium Conductance of Na/HCO(3) Cotransporter NBCn1 Decreases NMDA Receptor Function
por: Choi, Inyeong, et al.
Publicado: (2022)

Defective small intestinal anion secretion, dipeptide absorption, and intestinal failure in suckling NBCe1-deficient mice
por: Yu, Qin, et al.
Publicado: (2016)

Genistein Induces Increase in Fluid pH, Na(+) and HCO(3)(−) Concentration, SLC26A6 and SLC4A4 (NBCe1)-B Expression in the Uteri of Ovariectomized Rats
por: Chinigarzadeh, Asma, et al.
Publicado: (2014)

Altered Regulation of type 3 Na(+)/H(+) exchanger, type 1 Na(+)/HCO(3)(-) cotransporter, and Na(+),K(+)-ATPase in the Kidney of Rats with Experimental Rhabdomyolysis
por: Ma, Seong Kwon, et al.
Publicado: (2007)

Intracellular pH Regulation in Cultured Astrocytes from Rat Hippocampus : II. Electrogenic Na/HCO(3) Cotransport
por: Bevensee, Mark O., et al.
Publicado: (1997)

Sodium bicarbonate cotransporter NBCe2 gene variants increase sodium and bicarbonate transport in human renal proximal tubule cells
por: Gildea, John J., et al.
Publicado: (2018)

X-ray diffraction studies on merohedrally twinned Δ1–62NtNBCe1-A crystals of the sodium/bicarbonate cotransporter
por: Gill, Harindarpal S., et al.
Publicado: (2013)

The role of disease-linked residue glutamine-913 in support of the structure and function of the human electrogenic sodium/bicarbonate cotransporter NBCe1-A
por: Myers, Evan J., et al.
Publicado: (2018)

In vivo Overexpression of Electrogenic Sodium/Bicarbonate Cotransporter (NBCe1) by AAV9 Modifies the Cardiac Action Potential and the QT Interval in Mice
por: Di Mattía, Romina A., et al.
Publicado: (2022)

Ischemia/reperfusion injury in porcine intestine - Viability assessment
por: Strand-Amundsen, Runar J, et al.
Publicado: (2018)

Impacts of NaHCO(3) on β-Lactam Binding to PBP2a Protein Variants Associated with the NaHCO(3)-Responsive versus NaHCO(3)-Non-Responsive Phenotypes
por: Ersoy, Selvi C., et al.
Publicado: (2022)

Expression, Localization, and Effect of High Salt Intake on Electroneutral Na(+)/HCO(3)(–) Cotransporter NBCn2 in Rat Small Intestine: Implication in Intestinal NaCl Absorption
por: Wang, Jin-Lin, et al.
Publicado: (2019)

Effects of Urtica dioica on hepatic ischemia‐reperfusion injury in rats
por: Kandis, Hayati, et al.
Publicado: (2010)

Asymmetric dimethylarginine accumulates in the kidney during ischemia/reperfusion injury
por: Nakayama, Yosuke, et al.
Publicado: (2014)

Neuroprotective effect of atorvastatin in spinal cord ischemia-reperfusion injury
por: Nazli, Yunus, et al.
Publicado: (2015)

Treatment with dimethyl fumarate ameliorates liver ischemia/reperfusion injury
por: Takasu, Chie, et al.
Publicado: (2017)

S-Nitroso-N-Acetylcysteine Ameliorates Ischemia-Reperfusion Injury In The Steatotic Liver
por: Andraus, Wellington, et al.
Publicado: (2010)

Anticholestatic Effect of Bardoxolone Methyl on Hepatic Ischemia-reperfusion Injury in Rats
por: Kim, Joohyun, et al.
Publicado: (2020)

Hydrogen gas and preservation of intestinal stem cells in mesenteric ischemia and reperfusion
por: Yamamoto, Ryo, et al.
Publicado: (2022)

Haemoxygenase modulates cytokine induced neutrophil chemoattractant in hepatic ischemia reperfusion injury
por: Tapuria, Niteen, et al.
Publicado: (2016)

Morphological alterations and redox changes associated with hepatic warm ischemia-reperfusion injury
por: Jawad, Rim, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jq2aftpk7c70umr0ch5i52ht6k