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SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival

T-acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy with complicated heterogeneity. Although expression profiling reveals common elevated genes in distinct T-ALL subtypes, little is known about their functional role(s) and regulatory mechanism(s). We here show that SHQ1, a...

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Detalles Bibliográficos
Autores principales:	Su, Hexiu, Hu, Juncheng, Huang, Liang, Yang, Yang, Thenoz, Morgan, Kuchmiy, Anna, Hu, Yufeng, Li, Peng, Feng, Hui, Zhou, Yu, Taghon, Tom, Van Vlierberghe, Pieter, Qing, Guoliang, Chen, Zhichao, Liu, Hudan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189109/ https://www.ncbi.nlm.nih.gov/pubmed/30323192 http://dx.doi.org/10.1038/s41467-018-06523-4

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