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Hydrogen Sulfide Promotes Bone Homeostasis by Balancing Inflammatory Cytokine Signaling in CBS-Deficient Mice through an Epigenetic Mechanism
Previously, we have shown hyperhomocysteinemia (HHcy) to have a detrimental effect on bone remodeling, which is associated with osteoporosis. During transsulfuration, Hcy is metabolized into hydrogen sulfide (H(2)S), a gasotransmitter molecule known to regulate bone formation. Therefore, in the pres...
Autores principales: | Behera, Jyotirmaya, Kelly, Kimberly E., Voor, Michael J., Metreveli, Naira, Tyagi, Suresh C., Tyagi, Neetu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189133/ https://www.ncbi.nlm.nih.gov/pubmed/30323246 http://dx.doi.org/10.1038/s41598-018-33149-9 |
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