A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing

Phagocytosis is one of the earliest cellular functions, developing approximately 2 billion years ago. Although FcR-based phagocytic signaling is well-studied, how it originated from ancient phagocytosis is unknown. Lipid redistribution upregulates a phagocytic program recapitulating FcR-based phagoc...

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Detalles Bibliográficos
Autores principales: Mu, Libing, Tu, Zhongyuan, Miao, Lin, Ruan, Hefei, Kang, Ning, Hei, Yongzhen, Chen, Jiahuan, Wei, Wei, Gong, Fangling, Wang, Bingjie, Du, Yanan, Ma, Guanghui, Amerein, Matthias W., Xia, Tie, Shi, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189171/
https://www.ncbi.nlm.nih.gov/pubmed/30323235
http://dx.doi.org/10.1038/s41467-018-06744-7

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