Single cell RNA-seq reveals profound transcriptional similarity between Barrett’s oesophagus and oesophageal submucosal glands

Barrett’s oesophagus is a precursor of oesophageal adenocarcinoma. In this common condition, squamous epithelium in the oesophagus is replaced by columnar epithelium in response to acid reflux. Barrett’s oesophagus is highly heterogeneous and its relationships to normal tissues are unclear. Here we...

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Detalles Bibliográficos
Autores principales: Owen, Richard Peter, White, Michael Joseph, Severson, David Tyler, Braden, Barbara, Bailey, Adam, Goldin, Robert, Wang, Lai Mun, Ruiz-Puig, Carlos, Maynard, Nicholas David, Green, Angie, Piazza, Paolo, Buck, David, Middleton, Mark Ross, Ponting, Chris Paul, Schuster-Böckler, Benjamin, Lu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189174/
https://www.ncbi.nlm.nih.gov/pubmed/30323168
http://dx.doi.org/10.1038/s41467-018-06796-9

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