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PARP1 promote autophagy in cardiomyocytes via modulating FoxO3a transcription

Autophagy is a key regulatory process in maintaining cellular homoeostasis via lysosome degradation. Growing evidence reveals that poly(ADP-ribose) polymerase-1 (PARP1) is involved in the progression of many cardiovascular diseases. This study was undertaken to discuss the role of PARP1 in cardiomyo...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Xu, Wenjing, Zhang, Yanqing, Zhang, Fengxiao, Huang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189197/
https://www.ncbi.nlm.nih.gov/pubmed/30323296
http://dx.doi.org/10.1038/s41419-018-1108-6