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Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils
Neutrophils are critical for the defense against pathogens, in part through the extrusion of extracellular DNA traps, phagocytosis, and the production of reactive oxygen species. Neutrophils may also play an important role in the pathogenesis of rheumatoid arthritis (RA) through the activation of pr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189209/ https://www.ncbi.nlm.nih.gov/pubmed/30323221 http://dx.doi.org/10.1038/s41598-018-33385-z |