Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils

Neutrophils are critical for the defense against pathogens, in part through the extrusion of extracellular DNA traps, phagocytosis, and the production of reactive oxygen species. Neutrophils may also play an important role in the pathogenesis of rheumatoid arthritis (RA) through the activation of pr...

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Detalles Bibliográficos
Autores principales: Zhou, Yebin, An, Ling-Ling, Chaerkady, Raghothama, Mittereder, Nanette, Clarke, Lori, Cohen, Taylor S., Chen, Bo, Hess, Sonja, Sims, Gary P., Mustelin, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189209/
https://www.ncbi.nlm.nih.gov/pubmed/30323221
http://dx.doi.org/10.1038/s41598-018-33385-z

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