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The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasome-mediated degradation of PPARγ
Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-dependent transcription factor that regulates adipocyte differentiation and glucose homeostasis. The transcriptional activity of PPARγ is regulated not only by ligands but also by post-translational modifications (PTMs). In this st...
Autores principales: | Lee, Jae Min, Choi, Sun Sil, Lee, Yo Han, Khim, Keon Woo, Yoon, Sora, Kim, Byung-gyu, Nam, Dougu, Suh, Pann-Ghill, Myung, Kyungjae, Choi, Jang Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189217/ https://www.ncbi.nlm.nih.gov/pubmed/30323259 http://dx.doi.org/10.1038/s12276-018-0162-6 |
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