Cross-Dysregulation of O-GlcNAcylation and PI3K/AKT/mTOR Axis in Human Chronic Diseases

The hexosamine biosynthetic pathway (HBP) and the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway are considered as nutrient sensors that regulate several essential biological processes. The hexosamine biosynthetic pathway produces uridine diphosphate...

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Detalles Bibliográficos
Autores principales: Very, Ninon, Vercoutter-Edouart, Anne-Sophie, Lefebvre, Tony, Hardivillé, Stéphan, El Yazidi-Belkoura, Ikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189293/
https://www.ncbi.nlm.nih.gov/pubmed/30356686
http://dx.doi.org/10.3389/fendo.2018.00602

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