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Development of Adjuvant-Free Bivalent Food Poisoning Vaccine by Augmenting the Antigenicity of Clostridium perfringens Enterotoxin
Clostridium perfringens enterotoxin (CPE) is a common cause of food poisoning and hyperkalemia-associated death. Previously, we reported that fusion of pneumococcal surface protein A (PspA) to C-terminal fragment of CPE (C-CPE) efficiently bound mucosal epithelium so that PspA-specific immune respon...
Autores principales: | Suzuki, Hidehiko, Hosomi, Koji, Nasu, Ayaka, Kondoh, Masuo, Kunisawa, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189403/ https://www.ncbi.nlm.nih.gov/pubmed/30356722 http://dx.doi.org/10.3389/fimmu.2018.02320 |
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