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Fusion to Tetrahymena thermophila granule lattice protein 1 confers solubility to sexual stage malaria antigens in Escherichia coli

A transmission-blocking vaccine targeting the sexual stages of Plasmodium species could play a key role in eradicating malaria. Multiple studies have identified the P. falciparum proteins Pfs25 and Pfs48/45 as prime targets for transmission-blocking vaccines. Although significant advances have been...

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Detalles Bibliográficos
Autores principales: Agrawal, Alka, Bisharyan, Yelena, Papoyan, Ashot, Bednenko, Janna, Cardarelli, Joanna, Yao, Monica, Clark, Theodore, Berkmen, Mehmet, Ke, Na, Colussi, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189453/
https://www.ncbi.nlm.nih.gov/pubmed/30081196
http://dx.doi.org/10.1016/j.pep.2018.08.001