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Deficient O-GlcNAc Glycosylation Impairs Regulatory T Cell Differentiation and Notch Signaling in Autoimmune Hepatitis

Post-translational modifications such as glycosylation play an important role in the functions of homeostatic proteins, and are critical driving factors of several diseases; however, the role of glycosylation in autoimmune hepatitis is poorly understood. Here, we established an O-GlcNAc glycosylatio...

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Detalles Bibliográficos
Autores principales: Hao, Xiaohua, Li, Yufeng, Wang, Jianwen, Ma, Jiali, Zhao, Shuli, Ye, Xiaohui, He, Lingling, Yang, Junru, Gao, Meixin, Xiao, Fan, Wei, Hongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189470/
https://www.ncbi.nlm.nih.gov/pubmed/30356792
http://dx.doi.org/10.3389/fimmu.2018.02089