Cargando…

Biophysical Characterization of CD6—TCR/CD3 Interplay in T Cells

Activation of the T cell receptor (TCR) on the T cell through ligation with antigen-MHC complex of an antigen-presenting cell (APC) is an essential process in the activation of T cells and induction of the subsequent adaptive immune response. Upon activation, the TCR, together with its associated co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meddens, Marjolein B. M., Mennens, Svenja F. B., Celikkol, F. Burcu, te Riet, Joost, Kanger, Johannes S., Joosten, Ben, Witsenburg, J. Joris, Brock, Roland, Figdor, Carl G., Cambi, Alessandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189472/ https://www.ncbi.nlm.nih.gov/pubmed/30356797 http://dx.doi.org/10.3389/fimmu.2018.02333

Ejemplares similares

Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
por: Meddens, Marjolein B. M., et al.
Publicado: (2016)

Interplay between myosin IIA-mediated contractility and actin network integrity orchestrates podosome composition and oscillations
por: van den Dries, K., et al.
Publicado: (2013)

N-glycan mediated adhesion strengthening during pathogen-receptor binding revealed by cell-cell force spectroscopy
por: te Riet, Joost, et al.
Publicado: (2017)

Substrate stiffness influences phenotype and function of human antigen-presenting dendritic cells
por: Mennens, Svenja F. B., et al.
Publicado: (2017)

PLD-dependent phosphatidic acid microdomains are signaling platforms for podosome formation
por: Bolomini-Vittori, Matteo, et al.
Publicado: (2019)

Interleukin-4 Alters Early Phagosome Phenotype by Modulating Class I PI3K Dependent Lipid Remodeling and Protein Recruitment
por: de Keijzer, Sandra, et al.
Publicado: (2011)

The Multiple Faces of Prostaglandin E2 G-Protein Coupled Receptor Signaling during the Dendritic Cell Life Cycle
por: De Keijzer, Sandra, et al.
Publicado: (2013)

Stoichiometry of the T cell antigen receptor (TCR) complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains
Publicado: (1994)

Distinct Features of Canine Non-conventional CD4(−)CD8α(−) Double-Negative TCRαβ(+) vs. TCRγδ(+) T Cells
por: Rabiger, Friederike V., et al.
Publicado: (2019)

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer
por: Jahn, Lorenz, et al.
Publicado: (2016)

CD8β Increases CD8 Coreceptor Function and Participation in TCR–Ligand Binding
por: Renard, Valery, et al.
Publicado: (1996)

Structural and Biophysical Insights into the TCRαβ Complex in Chickens
por: Zhang, Lijie, et al.
Publicado: (2020)

CD5, an Undercover Regulator of TCR Signaling
por: Voisinne, Guillaume, et al.
Publicado: (2018)

Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex
Publicado: (1991)

CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity
por: Azzam, Hala S., et al.
Publicado: (1998)

CD3+CD16+NK1.1+B220+ large granular lymphocytes arise from both alpha- beta TCR+CD4-CD8- and gamma-delta TCR+CD4-CD8- cells
Publicado: (1994)

Generation of CD20-specific TCRs for TCR gene therapy of CD20(low) B-cell malignancies insusceptible to CD20-targeting antibodies
por: Jahn, Lorenz, et al.
Publicado: (2016)

TCR/CD3 coupling to Fas-based cytotoxicity
Publicado: (1995)

The CD3-Zeta Chimeric Antigen Receptor Overcomes TCR Hypo-Responsiveness of Human Terminal Late-Stage T Cells
por: Rappl, Gunter, et al.
Publicado: (2012)

Enhancing Efficacy of TCR-engineered CD4(+) T Cells Via Coexpression of CD8α
por: Anderson, Victoria E., et al.
Publicado: (2023)

Contrasted TCRβ Diversity of CD8(+) and CD8(−) T Cells in Rainbow Trout
por: Castro, Rosario, et al.
Publicado: (2013)

CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells
por: Cho, Jae-Ho, et al.
Publicado: (2016)

Intact CD100–CD72 Interaction Necessary for TCR-Induced T Cell Proliferation
por: Jiang, Xiaojun, et al.
Publicado: (2017)

Structural and Biophysical Insights into the Role of CD4 and CD8 in T Cell Activation
por: Li, Yili, et al.
Publicado: (2013)

The role of the different CD3γ domains in TCR expression and signaling
por: Garcillán, Beatriz, et al.
Publicado: (2022)

Collagen-Based Biomimetic Systems to Study the Biophysical Tumour Microenvironment
por: Cambi, Alessandra, et al.
Publicado: (2022)

Application of Biophysical Techniques to Cellular and Molecular Oncology
por: Lidke, Diane S., et al.
Publicado: (2023)

Atomic-resolution view of complete TCR-CD3 revealed
por: Chai, Jijie
Publicado: (2020)

Early molecular events induced by T cell receptor (TCR) signaling in immature CD4+ CD8+ thymocytes: increased synthesis of TCR-alpha protein is an early response to TCR signaling that compensates for TCR-alpha instability, improves TCR assembly, and parallels other indicators of positive selection
Publicado: (1995)

Dual-color superresolution microscopy reveals nanoscale organization of mechanosensory podosomes
por: van den Dries, K., et al.
Publicado: (2013)

Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes
por: Duong, Minh Ngoc, et al.
Publicado: (2019)

The Molecular Signature Underlying the Thymic Migration and Maturation of TCRαβ(+)CD4(+)CD8(-) Thymocytes
por: Teng, Fei, et al.
Publicado: (2011)

Lck Mediates Signal Transmission from CD59 to the TCR/CD3 Pathway in Jurkat T Cells
por: Lipp, Anna M., et al.
Publicado: (2014)

Treatment of B cells malignancies with anti-CD19 CAR+, TCR-, CD52- allogeneic T cells
por: Mannioui, Cécile Schiffer, et al.
Publicado: (2013)

An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice
por: Basu, Jayati, et al.
Publicado: (2022)

CD4 and CD8 T lymphocyte interplay in controlling tumor growth
por: Ostroumov, Dmitrij, et al.
Publicado: (2017)

The clone size of peripheral CD8 T cells is regulated by TCR promiscuity
por: Hao, Yi, et al.
Publicado: (2006)

Physical dissociation of the TCR-CD3 complex accompanies receptor ligation
Publicado: (1995)

Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells()
por: Borger, Jessica G., et al.
Publicado: (2014)

Ligand engaged TCR is triggered by Lck not associated with CD8 coreceptor
por: Casas, Javier, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7vesebs527ks6ujccrilap5k9f