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Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland
Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorders (EBV(+) T/NK LPD) encompass a heterogeneous group of disorders, including chronic active Epstein–Barr virus infection (CAEBV), Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH), systemic EBV(+) T-cell lympho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189562/ https://www.ncbi.nlm.nih.gov/pubmed/30356785 http://dx.doi.org/10.3389/fped.2018.00289 |
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author | Ai, Junhong Xie, Zhengde |
author_facet | Ai, Junhong Xie, Zhengde |
author_sort | Ai, Junhong |
collection | PubMed |
description | Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorders (EBV(+) T/NK LPD) encompass a heterogeneous group of disorders, including chronic active Epstein–Barr virus infection (CAEBV), Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH), systemic EBV(+) T-cell lymphoma of childhood and hydroa vacciniforme-like lymphoproliferative disorder (HVLPD) and so on, predominantly affecting children and young adults with high mortality. Patients with EBV(+) T/NK LPD have overlapping clinical symptoms as well as histologic and immunophenotypic features. In this review, we summarized the clinical features of EBV(+) T/NK LPD in Chinese patients from the published articles. |
format | Online Article Text |
id | pubmed-6189562 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-61895622018-10-23 Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland Ai, Junhong Xie, Zhengde Front Pediatr Pediatrics Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorders (EBV(+) T/NK LPD) encompass a heterogeneous group of disorders, including chronic active Epstein–Barr virus infection (CAEBV), Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH), systemic EBV(+) T-cell lymphoma of childhood and hydroa vacciniforme-like lymphoproliferative disorder (HVLPD) and so on, predominantly affecting children and young adults with high mortality. Patients with EBV(+) T/NK LPD have overlapping clinical symptoms as well as histologic and immunophenotypic features. In this review, we summarized the clinical features of EBV(+) T/NK LPD in Chinese patients from the published articles. Frontiers Media S.A. 2018-10-09 /pmc/articles/PMC6189562/ /pubmed/30356785 http://dx.doi.org/10.3389/fped.2018.00289 Text en Copyright © 2018 Ai and Xie. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Ai, Junhong Xie, Zhengde Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland |
title | Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland |
title_full | Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland |
title_fullStr | Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland |
title_full_unstemmed | Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland |
title_short | Epstein-Barr Virus-Positive T/NK-Cell Lymphoproliferative Diseases in Chinese Mainland |
title_sort | epstein-barr virus-positive t/nk-cell lymphoproliferative diseases in chinese mainland |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189562/ https://www.ncbi.nlm.nih.gov/pubmed/30356785 http://dx.doi.org/10.3389/fped.2018.00289 |
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