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The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics

The flow of liquids in centrifugal microfluidics is unidirectional and dominated by centrifugal and Coriolis forces (i.e., effective only at T-junctions). Developing mechanisms and discovering efficient techniques to propel liquids in any direction other than the direction of the centrifugal force h...

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Autores principales: Pishbin, Esmail, Eghbal, Manouchehr, Fakhari, Sepideh, Kazemzadeh, Amin, Navidbakhsh, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189857/
https://www.ncbi.nlm.nih.gov/pubmed/30404391
http://dx.doi.org/10.3390/mi7120215
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author Pishbin, Esmail
Eghbal, Manouchehr
Fakhari, Sepideh
Kazemzadeh, Amin
Navidbakhsh, Mehdi
author_facet Pishbin, Esmail
Eghbal, Manouchehr
Fakhari, Sepideh
Kazemzadeh, Amin
Navidbakhsh, Mehdi
author_sort Pishbin, Esmail
collection PubMed
description The flow of liquids in centrifugal microfluidics is unidirectional and dominated by centrifugal and Coriolis forces (i.e., effective only at T-junctions). Developing mechanisms and discovering efficient techniques to propel liquids in any direction other than the direction of the centrifugal force has been the subject of a large number of studies. The capillary force attained by specific surface treatments, pneumatic energy, active and passive flow reciprocation and Euler force have been previously introduced in order to manipulate the liquid flow and push it against the centrifugal force. Here, as a new method, the moment of inertia of the liquid inside a chamber in a centrifugal microfluidic platform is employed to manipulate the flow and propel the liquid passively towards the disc center. Furthermore, the effect of the moment of inertia on the liquid in a rectangular chamber is evaluated, both in theory and experiments, and the optimum geometry is defined. As an application of the introduced method, the moment of inertia of the liquid is used in order to mix two different dyed deionized (DI) waters; the mixing efficiency is evaluated and compared to similar mixing techniques. The results show the potential of the presented method for pumping liquids radially inward with relatively high flow rates (up to 23 mm(3)/s) and also efficient mixing in centrifugal microfluidic platforms.
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spelling pubmed-61898572018-11-01 The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics Pishbin, Esmail Eghbal, Manouchehr Fakhari, Sepideh Kazemzadeh, Amin Navidbakhsh, Mehdi Micromachines (Basel) Article The flow of liquids in centrifugal microfluidics is unidirectional and dominated by centrifugal and Coriolis forces (i.e., effective only at T-junctions). Developing mechanisms and discovering efficient techniques to propel liquids in any direction other than the direction of the centrifugal force has been the subject of a large number of studies. The capillary force attained by specific surface treatments, pneumatic energy, active and passive flow reciprocation and Euler force have been previously introduced in order to manipulate the liquid flow and push it against the centrifugal force. Here, as a new method, the moment of inertia of the liquid inside a chamber in a centrifugal microfluidic platform is employed to manipulate the flow and propel the liquid passively towards the disc center. Furthermore, the effect of the moment of inertia on the liquid in a rectangular chamber is evaluated, both in theory and experiments, and the optimum geometry is defined. As an application of the introduced method, the moment of inertia of the liquid is used in order to mix two different dyed deionized (DI) waters; the mixing efficiency is evaluated and compared to similar mixing techniques. The results show the potential of the presented method for pumping liquids radially inward with relatively high flow rates (up to 23 mm(3)/s) and also efficient mixing in centrifugal microfluidic platforms. MDPI 2016-12-02 /pmc/articles/PMC6189857/ /pubmed/30404391 http://dx.doi.org/10.3390/mi7120215 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pishbin, Esmail
Eghbal, Manouchehr
Fakhari, Sepideh
Kazemzadeh, Amin
Navidbakhsh, Mehdi
The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics
title The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics
title_full The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics
title_fullStr The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics
title_full_unstemmed The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics
title_short The Effect of Moment of Inertia on the Liquids in Centrifugal Microfluidics
title_sort effect of moment of inertia on the liquids in centrifugal microfluidics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189857/
https://www.ncbi.nlm.nih.gov/pubmed/30404391
http://dx.doi.org/10.3390/mi7120215
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