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Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings
Biomedical coatings are used to promote the wear resistance and the biocompatibility of a mechanical heart valve. An orbital shaking test was proposed to assess the durability of the coatings by the amount material eroded by the surrounding fluid. However, there is still a lack of understanding with...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189871/ http://dx.doi.org/10.3390/mi8040132 |
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author | Cherng, Wen-Jin Dong, Zuo-Syuan Chou, Chau-Chang Yeh, Chi-Hsiao Pan, Yu-Heng |
author_facet | Cherng, Wen-Jin Dong, Zuo-Syuan Chou, Chau-Chang Yeh, Chi-Hsiao Pan, Yu-Heng |
author_sort | Cherng, Wen-Jin |
collection | PubMed |
description | Biomedical coatings are used to promote the wear resistance and the biocompatibility of a mechanical heart valve. An orbital shaking test was proposed to assess the durability of the coatings by the amount material eroded by the surrounding fluid. However, there is still a lack of understanding with regards to the shaker’s rotating conditions and the corresponding physiological condition. This study implemented numerical simulations by establishing a fluid dynamic model to evaluate the intensity of the shear stress under various rotating speeds and diameters of the shaker. The results are valuable to conduct in vitro tests for estimating the performance of biomedical coatings under real hemodynamic conditions and can be applied to other fluid-contact implants. |
format | Online Article Text |
id | pubmed-6189871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61898712018-11-01 Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings Cherng, Wen-Jin Dong, Zuo-Syuan Chou, Chau-Chang Yeh, Chi-Hsiao Pan, Yu-Heng Micromachines (Basel) Article Biomedical coatings are used to promote the wear resistance and the biocompatibility of a mechanical heart valve. An orbital shaking test was proposed to assess the durability of the coatings by the amount material eroded by the surrounding fluid. However, there is still a lack of understanding with regards to the shaker’s rotating conditions and the corresponding physiological condition. This study implemented numerical simulations by establishing a fluid dynamic model to evaluate the intensity of the shear stress under various rotating speeds and diameters of the shaker. The results are valuable to conduct in vitro tests for estimating the performance of biomedical coatings under real hemodynamic conditions and can be applied to other fluid-contact implants. MDPI 2017-04-19 /pmc/articles/PMC6189871/ http://dx.doi.org/10.3390/mi8040132 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cherng, Wen-Jin Dong, Zuo-Syuan Chou, Chau-Chang Yeh, Chi-Hsiao Pan, Yu-Heng Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings |
title | Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings |
title_full | Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings |
title_fullStr | Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings |
title_full_unstemmed | Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings |
title_short | Hydrodynamic Simulation of an Orbital Shaking Test for the Degradation Assessment of Blood-Contact Biomedical Coatings |
title_sort | hydrodynamic simulation of an orbital shaking test for the degradation assessment of blood-contact biomedical coatings |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189871/ http://dx.doi.org/10.3390/mi8040132 |
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