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Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators
In this paper, we present the first microfluidic junctions for droplet generation directly engraved on lithium niobate crystals by micromachining techniques, preparatory to a fully integrated opto-microfluidics lab-on-chip system. In particular, laser ablation technique and the mechanical micromachi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190006/ http://dx.doi.org/10.3390/mi8060185 |
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author | Bettella, Giacomo Pozza, Gianluca Kroesen, Sebastian Zamboni, Riccardo Baggio, Enrico Montevecchi, Carlo Zaltron, Annamaria Gauthier-Manuel, Ludovic Mistura, Giampaolo Furlan, Claudio Chauvet, Mathieu Denz, Cornelia Sada, Cinzia |
author_facet | Bettella, Giacomo Pozza, Gianluca Kroesen, Sebastian Zamboni, Riccardo Baggio, Enrico Montevecchi, Carlo Zaltron, Annamaria Gauthier-Manuel, Ludovic Mistura, Giampaolo Furlan, Claudio Chauvet, Mathieu Denz, Cornelia Sada, Cinzia |
author_sort | Bettella, Giacomo |
collection | PubMed |
description | In this paper, we present the first microfluidic junctions for droplet generation directly engraved on lithium niobate crystals by micromachining techniques, preparatory to a fully integrated opto-microfluidics lab-on-chip system. In particular, laser ablation technique and the mechanical micromachining technique are exploited to realise microfluidic channels in T- and cross junction configurations. The quality of both lateral and bottom surfaces of the channels are therefore compared together with a detailed study of their roughness measured by means of atomic force microscopy in order to evaluate the final performance achievable in an optofluidic device. Finally, the microfluidics performances of these water-in-oil droplets generators are investigated depending on these micromachining techniques, with particular focus on a wide range of droplet generation rates. |
format | Online Article Text |
id | pubmed-6190006 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61900062018-11-01 Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators Bettella, Giacomo Pozza, Gianluca Kroesen, Sebastian Zamboni, Riccardo Baggio, Enrico Montevecchi, Carlo Zaltron, Annamaria Gauthier-Manuel, Ludovic Mistura, Giampaolo Furlan, Claudio Chauvet, Mathieu Denz, Cornelia Sada, Cinzia Micromachines (Basel) Article In this paper, we present the first microfluidic junctions for droplet generation directly engraved on lithium niobate crystals by micromachining techniques, preparatory to a fully integrated opto-microfluidics lab-on-chip system. In particular, laser ablation technique and the mechanical micromachining technique are exploited to realise microfluidic channels in T- and cross junction configurations. The quality of both lateral and bottom surfaces of the channels are therefore compared together with a detailed study of their roughness measured by means of atomic force microscopy in order to evaluate the final performance achievable in an optofluidic device. Finally, the microfluidics performances of these water-in-oil droplets generators are investigated depending on these micromachining techniques, with particular focus on a wide range of droplet generation rates. MDPI 2017-06-09 /pmc/articles/PMC6190006/ http://dx.doi.org/10.3390/mi8060185 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bettella, Giacomo Pozza, Gianluca Kroesen, Sebastian Zamboni, Riccardo Baggio, Enrico Montevecchi, Carlo Zaltron, Annamaria Gauthier-Manuel, Ludovic Mistura, Giampaolo Furlan, Claudio Chauvet, Mathieu Denz, Cornelia Sada, Cinzia Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators |
title | Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators |
title_full | Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators |
title_fullStr | Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators |
title_full_unstemmed | Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators |
title_short | Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators |
title_sort | lithium niobate micromachining for the fabrication of microfluidic droplet generators |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190006/ http://dx.doi.org/10.3390/mi8060185 |
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