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Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators

In this paper, we present the first microfluidic junctions for droplet generation directly engraved on lithium niobate crystals by micromachining techniques, preparatory to a fully integrated opto-microfluidics lab-on-chip system. In particular, laser ablation technique and the mechanical micromachi...

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Autores principales: Bettella, Giacomo, Pozza, Gianluca, Kroesen, Sebastian, Zamboni, Riccardo, Baggio, Enrico, Montevecchi, Carlo, Zaltron, Annamaria, Gauthier-Manuel, Ludovic, Mistura, Giampaolo, Furlan, Claudio, Chauvet, Mathieu, Denz, Cornelia, Sada, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190006/
http://dx.doi.org/10.3390/mi8060185
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author Bettella, Giacomo
Pozza, Gianluca
Kroesen, Sebastian
Zamboni, Riccardo
Baggio, Enrico
Montevecchi, Carlo
Zaltron, Annamaria
Gauthier-Manuel, Ludovic
Mistura, Giampaolo
Furlan, Claudio
Chauvet, Mathieu
Denz, Cornelia
Sada, Cinzia
author_facet Bettella, Giacomo
Pozza, Gianluca
Kroesen, Sebastian
Zamboni, Riccardo
Baggio, Enrico
Montevecchi, Carlo
Zaltron, Annamaria
Gauthier-Manuel, Ludovic
Mistura, Giampaolo
Furlan, Claudio
Chauvet, Mathieu
Denz, Cornelia
Sada, Cinzia
author_sort Bettella, Giacomo
collection PubMed
description In this paper, we present the first microfluidic junctions for droplet generation directly engraved on lithium niobate crystals by micromachining techniques, preparatory to a fully integrated opto-microfluidics lab-on-chip system. In particular, laser ablation technique and the mechanical micromachining technique are exploited to realise microfluidic channels in T- and cross junction configurations. The quality of both lateral and bottom surfaces of the channels are therefore compared together with a detailed study of their roughness measured by means of atomic force microscopy in order to evaluate the final performance achievable in an optofluidic device. Finally, the microfluidics performances of these water-in-oil droplets generators are investigated depending on these micromachining techniques, with particular focus on a wide range of droplet generation rates.
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spelling pubmed-61900062018-11-01 Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators Bettella, Giacomo Pozza, Gianluca Kroesen, Sebastian Zamboni, Riccardo Baggio, Enrico Montevecchi, Carlo Zaltron, Annamaria Gauthier-Manuel, Ludovic Mistura, Giampaolo Furlan, Claudio Chauvet, Mathieu Denz, Cornelia Sada, Cinzia Micromachines (Basel) Article In this paper, we present the first microfluidic junctions for droplet generation directly engraved on lithium niobate crystals by micromachining techniques, preparatory to a fully integrated opto-microfluidics lab-on-chip system. In particular, laser ablation technique and the mechanical micromachining technique are exploited to realise microfluidic channels in T- and cross junction configurations. The quality of both lateral and bottom surfaces of the channels are therefore compared together with a detailed study of their roughness measured by means of atomic force microscopy in order to evaluate the final performance achievable in an optofluidic device. Finally, the microfluidics performances of these water-in-oil droplets generators are investigated depending on these micromachining techniques, with particular focus on a wide range of droplet generation rates. MDPI 2017-06-09 /pmc/articles/PMC6190006/ http://dx.doi.org/10.3390/mi8060185 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bettella, Giacomo
Pozza, Gianluca
Kroesen, Sebastian
Zamboni, Riccardo
Baggio, Enrico
Montevecchi, Carlo
Zaltron, Annamaria
Gauthier-Manuel, Ludovic
Mistura, Giampaolo
Furlan, Claudio
Chauvet, Mathieu
Denz, Cornelia
Sada, Cinzia
Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators
title Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators
title_full Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators
title_fullStr Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators
title_full_unstemmed Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators
title_short Lithium Niobate Micromachining for the Fabrication of Microfluidic Droplet Generators
title_sort lithium niobate micromachining for the fabrication of microfluidic droplet generators
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190006/
http://dx.doi.org/10.3390/mi8060185
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