Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans

The nematode C. elegans (worm) is a small invertebrate animal widely used in studies related to fundamental biological processes, disease modelling, and drug discovery. Due to their small size and transparent body, these worms are highly suitable for experimental manipulations. In recent years sever...

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Detalles Bibliográficos
Autores principales: Gupta, Bhagwati P., Rezai, Pouya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190076/
https://www.ncbi.nlm.nih.gov/pubmed/30404296
http://dx.doi.org/10.3390/mi7070123
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author Gupta, Bhagwati P.
Rezai, Pouya
author_facet Gupta, Bhagwati P.
Rezai, Pouya
author_sort Gupta, Bhagwati P.
collection PubMed
description The nematode C. elegans (worm) is a small invertebrate animal widely used in studies related to fundamental biological processes, disease modelling, and drug discovery. Due to their small size and transparent body, these worms are highly suitable for experimental manipulations. In recent years several microfluidic devices and platforms have been developed to accelerate worm handling, phenotypic studies and screens. Here we review major tools and briefly discuss their usage in C. elegans research.
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spelling pubmed-61900762018-11-01 Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans Gupta, Bhagwati P. Rezai, Pouya Micromachines (Basel) Review The nematode C. elegans (worm) is a small invertebrate animal widely used in studies related to fundamental biological processes, disease modelling, and drug discovery. Due to their small size and transparent body, these worms are highly suitable for experimental manipulations. In recent years several microfluidic devices and platforms have been developed to accelerate worm handling, phenotypic studies and screens. Here we review major tools and briefly discuss their usage in C. elegans research. MDPI 2016-07-19 /pmc/articles/PMC6190076/ /pubmed/30404296 http://dx.doi.org/10.3390/mi7070123 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gupta, Bhagwati P.
Rezai, Pouya
Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans
title Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans
title_full Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans
title_fullStr Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans
title_full_unstemmed Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans
title_short Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans
title_sort microfluidic approaches for manipulating, imaging, and screening c. elegans
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190076/
https://www.ncbi.nlm.nih.gov/pubmed/30404296
http://dx.doi.org/10.3390/mi7070123
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