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Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method
Micromilling is a straightforward approach to the manufacture of polymer microfluidic devices for applications in chemistry and biology. This fabrication process reduces costs, provides a relatively simple user interface, and enables the fabrication of complex structures, which makes it ideal for th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190106/ https://www.ncbi.nlm.nih.gov/pubmed/30400454 http://dx.doi.org/10.3390/mi8090264 |
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author | Chen, Pin-Chuan Zhang, Ren-Hao Aue-u-lan, Yingyot Chang, Guo-En |
author_facet | Chen, Pin-Chuan Zhang, Ren-Hao Aue-u-lan, Yingyot Chang, Guo-En |
author_sort | Chen, Pin-Chuan |
collection | PubMed |
description | Micromilling is a straightforward approach to the manufacture of polymer microfluidic devices for applications in chemistry and biology. This fabrication process reduces costs, provides a relatively simple user interface, and enables the fabrication of complex structures, which makes it ideal for the development of prototypes. In this study, we investigated the influence of micromilling parameters on the surface roughness of a cyclic olefin copolymer (COC) substrate. We then employed factor analysis to determine the optimal cutting conditions. The parameters used in all experiments were the spindle speed, the feed rate, and the depth of cut. Roughness was measured using a stylus profilometer. The lowest roughness was 0.173 μm at a spindle speed of 20,000 rpm, feed rate of 300 mm/min, and cut depth of 20 μm. Factor analysis revealed that the feed rate has the greatest impact on surface quality, whereas the depth of cut has the least impact. |
format | Online Article Text |
id | pubmed-6190106 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61901062018-11-01 Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method Chen, Pin-Chuan Zhang, Ren-Hao Aue-u-lan, Yingyot Chang, Guo-En Micromachines (Basel) Article Micromilling is a straightforward approach to the manufacture of polymer microfluidic devices for applications in chemistry and biology. This fabrication process reduces costs, provides a relatively simple user interface, and enables the fabrication of complex structures, which makes it ideal for the development of prototypes. In this study, we investigated the influence of micromilling parameters on the surface roughness of a cyclic olefin copolymer (COC) substrate. We then employed factor analysis to determine the optimal cutting conditions. The parameters used in all experiments were the spindle speed, the feed rate, and the depth of cut. Roughness was measured using a stylus profilometer. The lowest roughness was 0.173 μm at a spindle speed of 20,000 rpm, feed rate of 300 mm/min, and cut depth of 20 μm. Factor analysis revealed that the feed rate has the greatest impact on surface quality, whereas the depth of cut has the least impact. MDPI 2017-08-29 /pmc/articles/PMC6190106/ /pubmed/30400454 http://dx.doi.org/10.3390/mi8090264 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chen, Pin-Chuan Zhang, Ren-Hao Aue-u-lan, Yingyot Chang, Guo-En Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method |
title | Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method |
title_full | Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method |
title_fullStr | Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method |
title_full_unstemmed | Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method |
title_short | Micromachining Microchannels on Cyclic Olefin Copolymer (COC) Substrates with the Taguchi Method |
title_sort | micromachining microchannels on cyclic olefin copolymer (coc) substrates with the taguchi method |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190106/ https://www.ncbi.nlm.nih.gov/pubmed/30400454 http://dx.doi.org/10.3390/mi8090264 |
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