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Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement

In the present work, an integrated optofluidic chip for fluid viscosity measurements in the range from 1 mPa·s to 100 mPa·s is proposed. The device allows the use of small sample volumes (<1 µL) and the measurement of viscosity as a function of temperature. Thanks to the precise control of the fo...

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Autores principales: Yang, Tie, Nava, Giovanni, Vitali, Valerio, Bragheri, Francesca, Osellame, Roberto, Bellini, Tommaso, Cristiani, Ilaria, Minzioni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190167/
http://dx.doi.org/10.3390/mi8030065
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author Yang, Tie
Nava, Giovanni
Vitali, Valerio
Bragheri, Francesca
Osellame, Roberto
Bellini, Tommaso
Cristiani, Ilaria
Minzioni, Paolo
author_facet Yang, Tie
Nava, Giovanni
Vitali, Valerio
Bragheri, Francesca
Osellame, Roberto
Bellini, Tommaso
Cristiani, Ilaria
Minzioni, Paolo
author_sort Yang, Tie
collection PubMed
description In the present work, an integrated optofluidic chip for fluid viscosity measurements in the range from 1 mPa·s to 100 mPa·s is proposed. The device allows the use of small sample volumes (<1 µL) and the measurement of viscosity as a function of temperature. Thanks to the precise control of the force exerted on dielectric spheres by optical beams, the viscosity of fluids is assessed by comparing the experimentally observed movement of dielectric beads produced by the optical forces with that expected by numerical calculations. The chip and the developed technique are validated by analyzing several fluids, such as Milli-Q water, ethanol and water–glycerol mixtures. The results show a good agreement between the experimental values and those reported in the literature. The extremely reduced volume of the sample required and the high flexibility of this technique make it a good candidate for measuring a wide range of viscosity values as well as for the analysis of nonlinear viscosity in complex fluids.
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spelling pubmed-61901672018-11-01 Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement Yang, Tie Nava, Giovanni Vitali, Valerio Bragheri, Francesca Osellame, Roberto Bellini, Tommaso Cristiani, Ilaria Minzioni, Paolo Micromachines (Basel) Article In the present work, an integrated optofluidic chip for fluid viscosity measurements in the range from 1 mPa·s to 100 mPa·s is proposed. The device allows the use of small sample volumes (<1 µL) and the measurement of viscosity as a function of temperature. Thanks to the precise control of the force exerted on dielectric spheres by optical beams, the viscosity of fluids is assessed by comparing the experimentally observed movement of dielectric beads produced by the optical forces with that expected by numerical calculations. The chip and the developed technique are validated by analyzing several fluids, such as Milli-Q water, ethanol and water–glycerol mixtures. The results show a good agreement between the experimental values and those reported in the literature. The extremely reduced volume of the sample required and the high flexibility of this technique make it a good candidate for measuring a wide range of viscosity values as well as for the analysis of nonlinear viscosity in complex fluids. MDPI 2017-02-23 /pmc/articles/PMC6190167/ http://dx.doi.org/10.3390/mi8030065 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Tie
Nava, Giovanni
Vitali, Valerio
Bragheri, Francesca
Osellame, Roberto
Bellini, Tommaso
Cristiani, Ilaria
Minzioni, Paolo
Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement
title Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement
title_full Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement
title_fullStr Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement
title_full_unstemmed Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement
title_short Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement
title_sort integrated optofluidic chip for low-volume fluid viscosity measurement
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190167/
http://dx.doi.org/10.3390/mi8030065
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