Cargando…
Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement
In the present work, an integrated optofluidic chip for fluid viscosity measurements in the range from 1 mPa·s to 100 mPa·s is proposed. The device allows the use of small sample volumes (<1 µL) and the measurement of viscosity as a function of temperature. Thanks to the precise control of the fo...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190167/ http://dx.doi.org/10.3390/mi8030065 |
_version_ | 1783363512020500480 |
---|---|
author | Yang, Tie Nava, Giovanni Vitali, Valerio Bragheri, Francesca Osellame, Roberto Bellini, Tommaso Cristiani, Ilaria Minzioni, Paolo |
author_facet | Yang, Tie Nava, Giovanni Vitali, Valerio Bragheri, Francesca Osellame, Roberto Bellini, Tommaso Cristiani, Ilaria Minzioni, Paolo |
author_sort | Yang, Tie |
collection | PubMed |
description | In the present work, an integrated optofluidic chip for fluid viscosity measurements in the range from 1 mPa·s to 100 mPa·s is proposed. The device allows the use of small sample volumes (<1 µL) and the measurement of viscosity as a function of temperature. Thanks to the precise control of the force exerted on dielectric spheres by optical beams, the viscosity of fluids is assessed by comparing the experimentally observed movement of dielectric beads produced by the optical forces with that expected by numerical calculations. The chip and the developed technique are validated by analyzing several fluids, such as Milli-Q water, ethanol and water–glycerol mixtures. The results show a good agreement between the experimental values and those reported in the literature. The extremely reduced volume of the sample required and the high flexibility of this technique make it a good candidate for measuring a wide range of viscosity values as well as for the analysis of nonlinear viscosity in complex fluids. |
format | Online Article Text |
id | pubmed-6190167 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61901672018-11-01 Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement Yang, Tie Nava, Giovanni Vitali, Valerio Bragheri, Francesca Osellame, Roberto Bellini, Tommaso Cristiani, Ilaria Minzioni, Paolo Micromachines (Basel) Article In the present work, an integrated optofluidic chip for fluid viscosity measurements in the range from 1 mPa·s to 100 mPa·s is proposed. The device allows the use of small sample volumes (<1 µL) and the measurement of viscosity as a function of temperature. Thanks to the precise control of the force exerted on dielectric spheres by optical beams, the viscosity of fluids is assessed by comparing the experimentally observed movement of dielectric beads produced by the optical forces with that expected by numerical calculations. The chip and the developed technique are validated by analyzing several fluids, such as Milli-Q water, ethanol and water–glycerol mixtures. The results show a good agreement between the experimental values and those reported in the literature. The extremely reduced volume of the sample required and the high flexibility of this technique make it a good candidate for measuring a wide range of viscosity values as well as for the analysis of nonlinear viscosity in complex fluids. MDPI 2017-02-23 /pmc/articles/PMC6190167/ http://dx.doi.org/10.3390/mi8030065 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yang, Tie Nava, Giovanni Vitali, Valerio Bragheri, Francesca Osellame, Roberto Bellini, Tommaso Cristiani, Ilaria Minzioni, Paolo Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement |
title | Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement |
title_full | Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement |
title_fullStr | Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement |
title_full_unstemmed | Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement |
title_short | Integrated Optofluidic Chip for Low-Volume Fluid Viscosity Measurement |
title_sort | integrated optofluidic chip for low-volume fluid viscosity measurement |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190167/ http://dx.doi.org/10.3390/mi8030065 |
work_keys_str_mv | AT yangtie integratedoptofluidicchipforlowvolumefluidviscositymeasurement AT navagiovanni integratedoptofluidicchipforlowvolumefluidviscositymeasurement AT vitalivalerio integratedoptofluidicchipforlowvolumefluidviscositymeasurement AT bragherifrancesca integratedoptofluidicchipforlowvolumefluidviscositymeasurement AT osellameroberto integratedoptofluidicchipforlowvolumefluidviscositymeasurement AT bellinitommaso integratedoptofluidicchipforlowvolumefluidviscositymeasurement AT cristianiilaria integratedoptofluidicchipforlowvolumefluidviscositymeasurement AT minzionipaolo integratedoptofluidicchipforlowvolumefluidviscositymeasurement |