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Study on Improving Thickness Uniformity of Microfluidic Chip Mold in the Electroforming Process
Electroformed microfluidic chip mold faces the problem of uneven thickness, which decreases the dimensional accuracy of the mold, and increases the production cost. To fabricate a mold with uniform thickness, two methods are investigated. Firstly, experiments are carried out to study how the ultraso...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190208/ https://www.ncbi.nlm.nih.gov/pubmed/30407379 http://dx.doi.org/10.3390/mi7010007 |
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author | Du, Liqun Yang, Tong Zhao, Ming Tao, Yousheng Luo, Lei Wang, Lei Liu, Chong |
author_facet | Du, Liqun Yang, Tong Zhao, Ming Tao, Yousheng Luo, Lei Wang, Lei Liu, Chong |
author_sort | Du, Liqun |
collection | PubMed |
description | Electroformed microfluidic chip mold faces the problem of uneven thickness, which decreases the dimensional accuracy of the mold, and increases the production cost. To fabricate a mold with uniform thickness, two methods are investigated. Firstly, experiments are carried out to study how the ultrasonic agitation affects the thickness uniformity of the mold. It is found that the thickness uniformity is maximally improved by about 30% after 2 h electroforming under 200 kHz and 500 W ultrasonic agitation. Secondly, adding a second cathode, a method suitable for long-time electroforming is studied by numerical simulation. The simulation results show that with a 4 mm width second cathode used, the thickness uniformity is improved by about 30% after 2 h of electroforming, and that with electroforming time extended, the thickness uniformity is improved more obviously. After 22 h electroforming, the thickness uniformity is increased by about 45%. Finally, by comparing two methods, the method of adding a second cathode is chosen, and a microfluidic chip mold is made with the help of a specially designed second cathode. The result shows that the thickness uniformity of the mold is increased by about 50%, which is in good agreement with the simulation results. |
format | Online Article Text |
id | pubmed-6190208 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61902082018-11-01 Study on Improving Thickness Uniformity of Microfluidic Chip Mold in the Electroforming Process Du, Liqun Yang, Tong Zhao, Ming Tao, Yousheng Luo, Lei Wang, Lei Liu, Chong Micromachines (Basel) Article Electroformed microfluidic chip mold faces the problem of uneven thickness, which decreases the dimensional accuracy of the mold, and increases the production cost. To fabricate a mold with uniform thickness, two methods are investigated. Firstly, experiments are carried out to study how the ultrasonic agitation affects the thickness uniformity of the mold. It is found that the thickness uniformity is maximally improved by about 30% after 2 h electroforming under 200 kHz and 500 W ultrasonic agitation. Secondly, adding a second cathode, a method suitable for long-time electroforming is studied by numerical simulation. The simulation results show that with a 4 mm width second cathode used, the thickness uniformity is improved by about 30% after 2 h of electroforming, and that with electroforming time extended, the thickness uniformity is improved more obviously. After 22 h electroforming, the thickness uniformity is increased by about 45%. Finally, by comparing two methods, the method of adding a second cathode is chosen, and a microfluidic chip mold is made with the help of a specially designed second cathode. The result shows that the thickness uniformity of the mold is increased by about 50%, which is in good agreement with the simulation results. MDPI 2016-01-13 /pmc/articles/PMC6190208/ /pubmed/30407379 http://dx.doi.org/10.3390/mi7010007 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Co mmons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Du, Liqun Yang, Tong Zhao, Ming Tao, Yousheng Luo, Lei Wang, Lei Liu, Chong Study on Improving Thickness Uniformity of Microfluidic Chip Mold in the Electroforming Process |
title | Study on Improving Thickness Uniformity of Microfluidic Chip Mold in the Electroforming Process |
title_full | Study on Improving Thickness Uniformity of Microfluidic Chip Mold in the Electroforming Process |
title_fullStr | Study on Improving Thickness Uniformity of Microfluidic Chip Mold in the Electroforming Process |
title_full_unstemmed | Study on Improving Thickness Uniformity of Microfluidic Chip Mold in the Electroforming Process |
title_short | Study on Improving Thickness Uniformity of Microfluidic Chip Mold in the Electroforming Process |
title_sort | study on improving thickness uniformity of microfluidic chip mold in the electroforming process |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190208/ https://www.ncbi.nlm.nih.gov/pubmed/30407379 http://dx.doi.org/10.3390/mi7010007 |
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