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1600 Parallel Microchamber Microfluidic Device for Fast Sample Array Preparation Using the Immiscibility of Two Liquids
We present a 1600 parallel microchamber microfluidic device for fast sample array preparation using the immiscibility of two liquids. The trapping efficiency and size of the arrayed sample in the microchambers of a parallel microfluidic device were analyzed at various flow rates. The trapping effici...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190353/ http://dx.doi.org/10.3390/mi8030063 |
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author | Kim, Chul Min Kim, Gyu Man |
author_facet | Kim, Chul Min Kim, Gyu Man |
author_sort | Kim, Chul Min |
collection | PubMed |
description | We present a 1600 parallel microchamber microfluidic device for fast sample array preparation using the immiscibility of two liquids. The trapping efficiency and size of the arrayed sample in the microchambers of a parallel microfluidic device were analyzed at various flow rates. The trapping efficiency of the sample was also inspected according to the position of the microchamber. Samples were successfully arrayed using the device. The trapping efficiency of the sample was 98.69% at 1 mL/h. The trapping efficiency and diameter of the sample decreased as the flow rate increased. Trapping efficiencies also changed according to the position of the microchambers. As the distance of the microchambers from the inlet increased, the sample trapping efficiency decreased. This tendency occurred more clearly at higher flow rates. |
format | Online Article Text |
id | pubmed-6190353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-61903532018-11-01 1600 Parallel Microchamber Microfluidic Device for Fast Sample Array Preparation Using the Immiscibility of Two Liquids Kim, Chul Min Kim, Gyu Man Micromachines (Basel) Article We present a 1600 parallel microchamber microfluidic device for fast sample array preparation using the immiscibility of two liquids. The trapping efficiency and size of the arrayed sample in the microchambers of a parallel microfluidic device were analyzed at various flow rates. The trapping efficiency of the sample was also inspected according to the position of the microchamber. Samples were successfully arrayed using the device. The trapping efficiency of the sample was 98.69% at 1 mL/h. The trapping efficiency and diameter of the sample decreased as the flow rate increased. Trapping efficiencies also changed according to the position of the microchambers. As the distance of the microchambers from the inlet increased, the sample trapping efficiency decreased. This tendency occurred more clearly at higher flow rates. MDPI 2017-02-23 /pmc/articles/PMC6190353/ http://dx.doi.org/10.3390/mi8030063 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kim, Chul Min Kim, Gyu Man 1600 Parallel Microchamber Microfluidic Device for Fast Sample Array Preparation Using the Immiscibility of Two Liquids |
title | 1600 Parallel Microchamber Microfluidic Device for Fast Sample Array Preparation Using the Immiscibility of Two Liquids |
title_full | 1600 Parallel Microchamber Microfluidic Device for Fast Sample Array Preparation Using the Immiscibility of Two Liquids |
title_fullStr | 1600 Parallel Microchamber Microfluidic Device for Fast Sample Array Preparation Using the Immiscibility of Two Liquids |
title_full_unstemmed | 1600 Parallel Microchamber Microfluidic Device for Fast Sample Array Preparation Using the Immiscibility of Two Liquids |
title_short | 1600 Parallel Microchamber Microfluidic Device for Fast Sample Array Preparation Using the Immiscibility of Two Liquids |
title_sort | 1600 parallel microchamber microfluidic device for fast sample array preparation using the immiscibility of two liquids |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190353/ http://dx.doi.org/10.3390/mi8030063 |
work_keys_str_mv | AT kimchulmin 1600parallelmicrochambermicrofluidicdeviceforfastsamplearraypreparationusingtheimmiscibilityoftwoliquids AT kimgyuman 1600parallelmicrochambermicrofluidicdeviceforfastsamplearraypreparationusingtheimmiscibilityoftwoliquids |