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Simultaneous determination of indapamide, perindopril and perindoprilat in human plasma or whole blood by UPLC-MS/MS and its pharmacokinetic application

Simple and sensitive methods were developed for the determination of indapamide, perindopril and its active metabolite perindoprilat in human plasma or whole blood by hyphenated ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS). Indapamide-d3, perindopril-d4 and perindoprilat-d4...

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Detalles Bibliográficos
Autores principales: Tao, Yi, Wang, Sheng, Wang, Lei, Song, Min, Hang, Taijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190495/
https://www.ncbi.nlm.nih.gov/pubmed/30345148
http://dx.doi.org/10.1016/j.jpha.2018.05.004