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Substrate specificity of the cypemycin decarboxylase CypD

The linaridin antibiotic cypemycin is a ribosomal synthesized and post-translationally modified peptide (RiPP) that possesses potent activity against mouse leukemia cells. This peptide natural product contains an S-[(Z)-2-aminovinyl]-d-cysteine (AviCys) moiety in the C-terminus. Formation of AviCys...

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Detalles Bibliográficos
Autores principales:	Ding, Wei, Mo, Tianlu, Mandalapu, Dhanaraju, Zhang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190514/ https://www.ncbi.nlm.nih.gov/pubmed/30345401 http://dx.doi.org/10.1016/j.synbio.2018.09.002

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