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Antidepressant and pro-motivational effects of repeated lamotrigine treatment in a rat model of depressive symptoms

BACKGROUND: The antiepileptic lamotrigine is approved for maintenance treatment of bipolar disorder and augmentation therapy in treatment-resistant depression. Previous preclinical investigations showed lamotrigine antidepressant-like effects without addressing its possible activity on motivational...

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Detalles Bibliográficos
Autores principales: Scheggi, Simona, Pelliccia, Teresa, Cuomo, Alessandro, De Montis, Maria Graziella, Gambarana, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190531/
https://www.ncbi.nlm.nih.gov/pubmed/30338306
http://dx.doi.org/10.1016/j.heliyon.2018.e00849