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Determination of asenapine in presence of its inactive metabolites in human plasma by LC-MS/MS

A highly selective and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay has been described for the determination of asenapine (ASE) in presence of its inactive metabolites N-desmethyl asenapine (DMA) and asenapine-N-glucuronide (ASG). ASE, and ASE 13C-d3, used as internal st...

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Detalles Bibliográficos
Autores principales: Patel, Nirav P., Sanyal, Mallika, Sharma, Naveen, Patel, Dinesh S., Shrivastav, Pranav S., Patel, Bhavin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190535/
https://www.ncbi.nlm.nih.gov/pubmed/30345149
http://dx.doi.org/10.1016/j.jpha.2018.06.002

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