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Recent advancements in the use of exosomes as drug delivery systems

Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many studies sho...

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Detalles Bibliográficos
Autores principales: Bunggulawa, Edwin J., Wang, Wei, Yin, Tieying, Wang, Nan, Durkan, Colm, Wang, Yazhou, Wang, Guixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190562/
https://www.ncbi.nlm.nih.gov/pubmed/30326899
http://dx.doi.org/10.1186/s12951-018-0403-9
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author Bunggulawa, Edwin J.
Wang, Wei
Yin, Tieying
Wang, Nan
Durkan, Colm
Wang, Yazhou
Wang, Guixue
author_facet Bunggulawa, Edwin J.
Wang, Wei
Yin, Tieying
Wang, Nan
Durkan, Colm
Wang, Yazhou
Wang, Guixue
author_sort Bunggulawa, Edwin J.
collection PubMed
description Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many studies show that exosome can efficiently deliver many different kinds of cargo to the target cell. Therefore, they are often used to deliver therapeutic cargo for treatment. The exosomes that have been used include both natural ones and those that have been modified with other substances to increase the delivery ability. This article provides a review of both exosomes derived from various cells and modified exosome and their ability in delivering the many kinds of cargo to the target cell.
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spelling pubmed-61905622018-10-23 Recent advancements in the use of exosomes as drug delivery systems Bunggulawa, Edwin J. Wang, Wei Yin, Tieying Wang, Nan Durkan, Colm Wang, Yazhou Wang, Guixue J Nanobiotechnology Review Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many studies show that exosome can efficiently deliver many different kinds of cargo to the target cell. Therefore, they are often used to deliver therapeutic cargo for treatment. The exosomes that have been used include both natural ones and those that have been modified with other substances to increase the delivery ability. This article provides a review of both exosomes derived from various cells and modified exosome and their ability in delivering the many kinds of cargo to the target cell. BioMed Central 2018-10-16 /pmc/articles/PMC6190562/ /pubmed/30326899 http://dx.doi.org/10.1186/s12951-018-0403-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Bunggulawa, Edwin J.
Wang, Wei
Yin, Tieying
Wang, Nan
Durkan, Colm
Wang, Yazhou
Wang, Guixue
Recent advancements in the use of exosomes as drug delivery systems
title Recent advancements in the use of exosomes as drug delivery systems
title_full Recent advancements in the use of exosomes as drug delivery systems
title_fullStr Recent advancements in the use of exosomes as drug delivery systems
title_full_unstemmed Recent advancements in the use of exosomes as drug delivery systems
title_short Recent advancements in the use of exosomes as drug delivery systems
title_sort recent advancements in the use of exosomes as drug delivery systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190562/
https://www.ncbi.nlm.nih.gov/pubmed/30326899
http://dx.doi.org/10.1186/s12951-018-0403-9
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