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Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma

PURPOSE: We investigated the effect of carbonic anhydrase IX (CA IX) inhibitor under hypoxia and normoxia in SaOS2 human osteosarcoma cell line. We also evaluated the expression of CA IX in 27 patients diagnosed with osteosarcoma. MATERIALS AND METHODS: CA IX expression in SaOS2 cells cultured under...

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Detalles Bibliográficos
Autores principales:	Okuno, Kazuma, Matsubara, Takao, Nakamura, Tomoki, Iino, Takahiro, Kakimoto, Takuya, Asanuma, Kunihiro, Matsumine, Akihiko, Sudo, Akihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190629/ https://www.ncbi.nlm.nih.gov/pubmed/30349321 http://dx.doi.org/10.2147/OTT.S177605

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