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Tcf7l1 directly regulates cardiomyocyte differentiation in embryonic stem cells

The T-cell factor/lymphoid enhancer factor (TCF/LEF) family protein Tcf7l1 is highly abundant in embryonic stem cells (ESCs), regulating pluripotency and preparing epiblasts for further differentiation. Defects in the cardiovascular system in Tcf7l1-null mouse were considered secondary to mesoderm m...

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Detalles Bibliográficos
Autores principales: Liang, Rui, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190650/
https://www.ncbi.nlm.nih.gov/pubmed/30326964
http://dx.doi.org/10.1186/s13287-018-1015-x