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Genetics and sex influence peripheral and central innate immune responses and blood-brain barrier integrity
Lipopolysaccharide (LPS) is a stimulator of the innate immune system and is routinely used in animal models to study blood-brain barrier (BBB) dysfunction under inflammatory conditions. It is appreciated that both humans and mice have sexually dimorphic immune responses, which could influence the br...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191122/ https://www.ncbi.nlm.nih.gov/pubmed/30325961 http://dx.doi.org/10.1371/journal.pone.0205769 |