Cationic nanoparticle as an inhibitor of cell-free DNA-induced inflammation

Cell-free DNA (cfDNA) released from damaged or dead cells can activate DNA sensors that exacerbate the pathogenesis of rheumatoid arthritis (RA). Here we show that ~40 nm cationic nanoparticles (cNP) can scavenge cfDNA derived from RA patients and inhibit the activation of primary synovial fluid mon...

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Detalles Bibliográficos
Autores principales: Liang, Huiyi, Peng, Bo, Dong, Cong, Liu, Lixin, Mao, Jiaji, Wei, Song, Wang, Xinlu, Xu, Hanshi, Shen, Jun, Mao, Hai-Quan, Gao, Xiaohu, Leong, Kam W., Chen, Yongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191420/
https://www.ncbi.nlm.nih.gov/pubmed/30327464
http://dx.doi.org/10.1038/s41467-018-06603-5

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