Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors

A tissue engineered oesophagus could overcome limitations associated with oesophageal substitution. Combining decellularized scaffolds with patient-derived cells shows promise for regeneration of tissue defects. In this proof-of-principle study, a two-stage approach for generation of a bio-artificia...

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Detalles Bibliográficos
Autores principales: Urbani, Luca, Camilli, Carlotta, Phylactopoulos, Demetra-Ellie, Crowley, Claire, Natarajan, Dipa, Scottoni, Federico, Maghsoudlou, Panayiotis, McCann, Conor J., Pellegata, Alessandro Filippo, Urciuolo, Anna, Deguchi, Koichi, Khalaf, Sahira, Aruta, Salvatore Ferdinando, Signorelli, Maria Cristina, Kiely, David, Hannon, Edward, Trevisan, Matteo, Wong, Rui Rachel, Baradez, Marc Olivier, Moulding, Dale, Virasami, Alex, Gjinovci, Asllan, Loukogeorgakis, Stavros, Mantero, Sara, Thapar, Nikhil, Sebire, Neil, Eaton, Simon, Lowdell, Mark, Cossu, Giulio, Bonfanti, Paola, De Coppi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191423/
https://www.ncbi.nlm.nih.gov/pubmed/30327457
http://dx.doi.org/10.1038/s41467-018-06385-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191423/
https://www.ncbi.nlm.nih.gov/pubmed/30327457
http://dx.doi.org/10.1038/s41467-018-06385-w

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