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Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors
A tissue engineered oesophagus could overcome limitations associated with oesophageal substitution. Combining decellularized scaffolds with patient-derived cells shows promise for regeneration of tissue defects. In this proof-of-principle study, a two-stage approach for generation of a bio-artificia...
Autores principales: | Urbani, Luca, Camilli, Carlotta, Phylactopoulos, Demetra-Ellie, Crowley, Claire, Natarajan, Dipa, Scottoni, Federico, Maghsoudlou, Panayiotis, McCann, Conor J., Pellegata, Alessandro Filippo, Urciuolo, Anna, Deguchi, Koichi, Khalaf, Sahira, Aruta, Salvatore Ferdinando, Signorelli, Maria Cristina, Kiely, David, Hannon, Edward, Trevisan, Matteo, Wong, Rui Rachel, Baradez, Marc Olivier, Moulding, Dale, Virasami, Alex, Gjinovci, Asllan, Loukogeorgakis, Stavros, Mantero, Sara, Thapar, Nikhil, Sebire, Neil, Eaton, Simon, Lowdell, Mark, Cossu, Giulio, Bonfanti, Paola, De Coppi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191423/ https://www.ncbi.nlm.nih.gov/pubmed/30327457 http://dx.doi.org/10.1038/s41467-018-06385-w |
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