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IgG-mediated immune suppression in mice is epitope specific except during high epitope density conditions

Specific IgG antibodies, passively administered together with erythrocytes, suppress antibody responses against the erythrocytes. Although used to prevent alloimmunization in Rhesus (Rh)D-negative women carrying RhD-positive fetuses, the mechanism behind is not understood. In mice, IgG suppresses ef...

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Detalles Bibliográficos
Autores principales: Xu, Hui, Zhang, Lu, Heyman, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191431/
https://www.ncbi.nlm.nih.gov/pubmed/30327481
http://dx.doi.org/10.1038/s41598-018-33087-6