Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors

Germline BRCA1 mutations predispose women to breast and ovarian cancer. BRCA1, a large protein with multiple functional domains, interacts with numerous proteins involved in many important biological processes and pathways. However, to date, the role of BRCA1 interactions at specific stages in the p...

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Detalles Bibliográficos
Autores principales: Choi, Eun Kyung, Lim, Jeong-A, Kim, Jong Kwang, Jang, Moon Sun, Kim, Sun Eui, Baek, Hye Jung, Park, Eun Jung, Kim, Tae Hyun, Deng, Chu-Xia, Wang, Rui-Hong, Kim, Sang Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191436/
https://www.ncbi.nlm.nih.gov/pubmed/30327455
http://dx.doi.org/10.1038/s12276-018-0169-z

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