Structural basis for arginine glycosylation of host substrates by bacterial effector proteins

The bacterial effector proteins SseK and NleB glycosylate host proteins on arginine residues, leading to reduced NF-κB-dependent responses to infection. Salmonella SseK1 and SseK2 are E. coli NleB1 orthologs that behave as NleB1-like GTs, although they differ in protein substrate specificity. Here w...

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Detalles Bibliográficos
Autores principales: Park, Jun Bae, Kim, Young Hun, Yoo, Youngki, Kim, Juyeon, Jun, Sung-Hoon, Cho, Jin Won, El Qaidi, Samir, Walpole, Samuel, Monaco, Serena, García-García, Ana A., Wu, Miaomiao, Hays, Michael P., Hurtado-Guerrero, Ramon, Angulo, Jesus, Hardwidge, Philip R., Shin, Jeon-Soo, Cho, Hyun-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191443/
https://www.ncbi.nlm.nih.gov/pubmed/30327479
http://dx.doi.org/10.1038/s41467-018-06680-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191443/
https://www.ncbi.nlm.nih.gov/pubmed/30327479
http://dx.doi.org/10.1038/s41467-018-06680-6

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