NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies

Neisseria meningitidis serogroup B (MenB) is a major cause of sepsis and invasive meningococcal disease. A multicomponent vaccine, 4CMenB, is approved for protection against MenB. Neisserial adhesin A (NadA) is one of the main vaccine antigens, acts in host cell adhesion, and may influence colonizat...

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Detalles Bibliográficos
Autores principales: Liguori, Alessia, Dello Iacono, Lucia, Maruggi, Giulietta, Benucci, Barbara, Merola, Marcello, Lo Surdo, Paola, López-Sagaseta, Jacinto, Pizza, Mariagrazia, Malito, Enrico, Bottomley, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191539/
https://www.ncbi.nlm.nih.gov/pubmed/30327444
http://dx.doi.org/10.1128/mBio.01914-18

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