Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation

Late in the HIV-1 replication cycle, the viral structural protein Gag is targeted to virus assembly sites at the plasma membrane of infected cells. The capsid (CA) domain of Gag plays a critical role in the formation of the hexameric Gag lattice in the immature virion, and, during particle release,...

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Detalles Bibliográficos
Autores principales: Novikova, Mariia, Adams, Lucas J., Fontana, Juan, Gres, Anna T., Balasubramaniam, Muthukumar, Winkler, Dennis C., Kudchodkar, Sagar B., Soheilian, Ferri, Sarafianos, Stefan G., Steven, Alasdair C., Freed, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191540/
https://www.ncbi.nlm.nih.gov/pubmed/30327442
http://dx.doi.org/10.1128/mBio.01567-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191540/
https://www.ncbi.nlm.nih.gov/pubmed/30327442
http://dx.doi.org/10.1128/mBio.01567-18

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