A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma

A 36-year old man was referred to our hospital due to isolated chronic cough that was refractory to anti-asthma medications, including inhaled corticosteroids/long-acting β(2) agonists. Chest X-ray showed diffuse nodular and enhanced vascular shadows with Kerley lines in both lungs. A blood analysis...

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Autores principales: Okayama, Minami, Kanemitsu, Yoshihiro, Oguri, Tetsuya, Asano, Takamitsu, Fukuda, Satoshi, Ohkubo, Hirotsugu, Takemura, Masaya, Maeno, Ken, Ito, Yutaka, Niimi, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191591/
https://www.ncbi.nlm.nih.gov/pubmed/29780119
http://dx.doi.org/10.2169/internalmedicine.0572-17
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author Okayama, Minami
Kanemitsu, Yoshihiro
Oguri, Tetsuya
Asano, Takamitsu
Fukuda, Satoshi
Ohkubo, Hirotsugu
Takemura, Masaya
Maeno, Ken
Ito, Yutaka
Niimi, Akio
author_facet Okayama, Minami
Kanemitsu, Yoshihiro
Oguri, Tetsuya
Asano, Takamitsu
Fukuda, Satoshi
Ohkubo, Hirotsugu
Takemura, Masaya
Maeno, Ken
Ito, Yutaka
Niimi, Akio
author_sort Okayama, Minami
collection PubMed
description A 36-year old man was referred to our hospital due to isolated chronic cough that was refractory to anti-asthma medications, including inhaled corticosteroids/long-acting β(2) agonists. Chest X-ray showed diffuse nodular and enhanced vascular shadows with Kerley lines in both lungs. A blood analysis showed elevated serum carcinoembryonic antigen (CEA) and CA19-9 levels. A transbronchial biopsy revealed well to moderately differentiated adenocarcinoma, the origin of which was immunohistochemically suspected to be the gastrointestinal tract. Colonoscopy confirmed the diagnosis of primary rectum carcinoma. Pulmonary lymphangitic carcinomatosis was therefore regarded as the origin of the cough. Lymphangitic carcinomatosis is an uncommon diagnosis but important to consider in patients with persistent cough.
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spelling pubmed-61915912018-10-19 A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma Okayama, Minami Kanemitsu, Yoshihiro Oguri, Tetsuya Asano, Takamitsu Fukuda, Satoshi Ohkubo, Hirotsugu Takemura, Masaya Maeno, Ken Ito, Yutaka Niimi, Akio Intern Med Case Report A 36-year old man was referred to our hospital due to isolated chronic cough that was refractory to anti-asthma medications, including inhaled corticosteroids/long-acting β(2) agonists. Chest X-ray showed diffuse nodular and enhanced vascular shadows with Kerley lines in both lungs. A blood analysis showed elevated serum carcinoembryonic antigen (CEA) and CA19-9 levels. A transbronchial biopsy revealed well to moderately differentiated adenocarcinoma, the origin of which was immunohistochemically suspected to be the gastrointestinal tract. Colonoscopy confirmed the diagnosis of primary rectum carcinoma. Pulmonary lymphangitic carcinomatosis was therefore regarded as the origin of the cough. Lymphangitic carcinomatosis is an uncommon diagnosis but important to consider in patients with persistent cough. The Japanese Society of Internal Medicine 2018-05-18 2018-09-15 /pmc/articles/PMC6191591/ /pubmed/29780119 http://dx.doi.org/10.2169/internalmedicine.0572-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Okayama, Minami
Kanemitsu, Yoshihiro
Oguri, Tetsuya
Asano, Takamitsu
Fukuda, Satoshi
Ohkubo, Hirotsugu
Takemura, Masaya
Maeno, Ken
Ito, Yutaka
Niimi, Akio
A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma
title A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma
title_full A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma
title_fullStr A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma
title_full_unstemmed A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma
title_short A Rare Case of Isolated Chronic Cough Caused by Pulmonary Lymphangitic Carcinomatosis as a Primary Manifestation of Rectum Carcinoma
title_sort rare case of isolated chronic cough caused by pulmonary lymphangitic carcinomatosis as a primary manifestation of rectum carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191591/
https://www.ncbi.nlm.nih.gov/pubmed/29780119
http://dx.doi.org/10.2169/internalmedicine.0572-17
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