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Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck

Throughout history, humans have been afflicted by parasitic worms, and eggs are readily detected in archaeological deposits. This study integrated parasitological and ancient DNA methods with a large sample set dating between Neolithic and Early Modern periods to explore the utility of molecular arc...

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Autores principales: Flammer, Patrik G., Dellicour, Simon, Preston, Stephen G., Rieger, Dirk, Warren, Sylvia, Tan, Cedric K. W., Nicholson, Rebecca, Přichystalová, Renáta, Bleicher, Niels, Wahl, Joachim, Faria, Nuno R., Pybus, Oliver G., Pollard, Mark, Smith, Adrian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191690/
https://www.ncbi.nlm.nih.gov/pubmed/30282648
http://dx.doi.org/10.1098/rspb.2018.0991
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author Flammer, Patrik G.
Dellicour, Simon
Preston, Stephen G.
Rieger, Dirk
Warren, Sylvia
Tan, Cedric K. W.
Nicholson, Rebecca
Přichystalová, Renáta
Bleicher, Niels
Wahl, Joachim
Faria, Nuno R.
Pybus, Oliver G.
Pollard, Mark
Smith, Adrian L.
author_facet Flammer, Patrik G.
Dellicour, Simon
Preston, Stephen G.
Rieger, Dirk
Warren, Sylvia
Tan, Cedric K. W.
Nicholson, Rebecca
Přichystalová, Renáta
Bleicher, Niels
Wahl, Joachim
Faria, Nuno R.
Pybus, Oliver G.
Pollard, Mark
Smith, Adrian L.
author_sort Flammer, Patrik G.
collection PubMed
description Throughout history, humans have been afflicted by parasitic worms, and eggs are readily detected in archaeological deposits. This study integrated parasitological and ancient DNA methods with a large sample set dating between Neolithic and Early Modern periods to explore the utility of molecular archaeoparasitology as a new approach to study the past. Molecular analyses provided unequivocal species-level parasite identification and revealed location-specific epidemiological signatures. Faecal–oral transmitted nematodes (Ascaris lumbricoides and Trichuris trichiura) were ubiquitous across time and space. By contrast, high numbers of food-associated cestodes (Diphyllobothrium latum and Taenia saginata) were restricted to medieval Lübeck. The presence of these cestodes and changes in their prevalence at approximately 1300 CE indicate substantial alterations in diet or parasite availability. Trichuris trichiura ITS-1 sequences grouped into two clades; one ubiquitous and one restricted to medieval Lübeck and Bristol. The high sequence diversity of T.t.ITS-1 detected in Lübeck is consistent with its importance as a Hanseatic trading centre. Collectively, these results introduce molecular archaeoparasitology as an artefact-independent source of historical evidence.
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spelling pubmed-61916902018-10-30 Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck Flammer, Patrik G. Dellicour, Simon Preston, Stephen G. Rieger, Dirk Warren, Sylvia Tan, Cedric K. W. Nicholson, Rebecca Přichystalová, Renáta Bleicher, Niels Wahl, Joachim Faria, Nuno R. Pybus, Oliver G. Pollard, Mark Smith, Adrian L. Proc Biol Sci Palaeobiology Throughout history, humans have been afflicted by parasitic worms, and eggs are readily detected in archaeological deposits. This study integrated parasitological and ancient DNA methods with a large sample set dating between Neolithic and Early Modern periods to explore the utility of molecular archaeoparasitology as a new approach to study the past. Molecular analyses provided unequivocal species-level parasite identification and revealed location-specific epidemiological signatures. Faecal–oral transmitted nematodes (Ascaris lumbricoides and Trichuris trichiura) were ubiquitous across time and space. By contrast, high numbers of food-associated cestodes (Diphyllobothrium latum and Taenia saginata) were restricted to medieval Lübeck. The presence of these cestodes and changes in their prevalence at approximately 1300 CE indicate substantial alterations in diet or parasite availability. Trichuris trichiura ITS-1 sequences grouped into two clades; one ubiquitous and one restricted to medieval Lübeck and Bristol. The high sequence diversity of T.t.ITS-1 detected in Lübeck is consistent with its importance as a Hanseatic trading centre. Collectively, these results introduce molecular archaeoparasitology as an artefact-independent source of historical evidence. The Royal Society 2018-10-10 2018-10-03 /pmc/articles/PMC6191690/ /pubmed/30282648 http://dx.doi.org/10.1098/rspb.2018.0991 Text en © 2018 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Palaeobiology
Flammer, Patrik G.
Dellicour, Simon
Preston, Stephen G.
Rieger, Dirk
Warren, Sylvia
Tan, Cedric K. W.
Nicholson, Rebecca
Přichystalová, Renáta
Bleicher, Niels
Wahl, Joachim
Faria, Nuno R.
Pybus, Oliver G.
Pollard, Mark
Smith, Adrian L.
Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
title Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
title_full Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
title_fullStr Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
title_full_unstemmed Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
title_short Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
title_sort molecular archaeoparasitology identifies cultural changes in the medieval hanseatic trading centre of lübeck
topic Palaeobiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191690/
https://www.ncbi.nlm.nih.gov/pubmed/30282648
http://dx.doi.org/10.1098/rspb.2018.0991
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